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Product Details
PA5-139976
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human BLOC1S3
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2926978
Product Specific Information
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: LPPLVVQRES AEEAWGTEEA PAPAPARSLL QLRLAES
Target Information
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: biogenesis of lysosomal organelles complex-1, subunit 3; Biogenesis of lysosome-related organelles complex 1 subunit 3; biogenesis of lysosome-related organelles complex-1, subunit 3; BLOC-1 subunit 3; reduced pigmentation, mouse, homolog of
Gene Aliases: BLOC1S3; BLOS3; HPS8; RP
UniProt ID: (Human) Q6QNY0
Entrez Gene ID: (Human) 388552
eye development
anterograde axonal transport
platelet activation
neuron projection development
melanosome transport
melanosome organization
positive regulation of natural killer cell activation
secretion of lysosomal enzymes
endosome to melanosome transport
response to drug
pigmentation
anterograde synaptic vesicle transport
platelet dense granule organization
protein transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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