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FIGURE: 1 / 3
BMP-8A Antibody (PA5-36435) in WB
Western blot analysis of BMP-8A in Lane 1: SGC7901 whole cell lysate (40 µg), Lane 2: L02 whole cell lysate (40 µg), Lane 3: the Heart tissue lysate of rat (40 µg), Lane 4: the Kidney tissue lysate of mouse (40 µg), Lane 5: PC12 whole cell lysate (40 µg), Lane 6: CT26 whole cell lysate (40 µg). Samples were incubated with BMP-8A polyclonal antibody (Product # PA5-36435) at a dilution of 1:500.
Product Details
PA5-36435
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 264-321 of human BMP-8A
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2553524
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 45 kDa. It may cross-react with BMP-8B protein.
Purity is >95% by SDS-PAGE.
Target Information
Bone morphogenic proteins (BMPs) are members of the TGF beta superfamily. BMPs are involved in the induction of cartilage and bone formation.BMP-8 is thought to be involved in early development, as detectable expression has not been found in adult organs. Two BMP-8 proteins exist, namely BMP-8A and BMP-8B (also designated OP-2), and are encoded by two distinct genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BMP; BMP-8A; BMP8B; Bone morphogenetic protein; Bone morphogenetic protein 8A; OP-2; Osteogenic protein 2
Gene Aliases: Bmp-8; Bmp7r1; Bmp8; BMP8A; OP-2; OP2
UniProt ID: (Human) Q7Z5Y6, (Mouse) P34821
Entrez Gene ID: (Human) 353500, (Mouse) 12163, (Rat) 680931
Molecular Function:
growth factor
ossification
diet induced thermogenesis
positive regulation of pathway-restricted SMAD protein phosphorylation
BMP signaling pathway
growth
regulation of apoptotic process
regulation of MAPK cascade
negative regulation of insulin secretion
cell development
cartilage development
SMAD protein signal transduction
regulation of energy homeostasis
osteoblast differentiation
transforming growth factor beta receptor signaling pathway
multicellular organism development
germ cell development
spermatogenesis
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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