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Invitrogen
BMP1 Polyclonal Antibody
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Product Details
PA5-37844
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-DTIVPKYEVNGVK, from the internal region of BMP1 (aa284-296)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with dog, pig and cow based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
Target Information
This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BMP; BMP-1; Bone morphogenetic protein; Bone morphogenetic protein 1; FLJ44432; Mammalian tolloid protein; mTld; PCP; pCP-2; procollagen C-endopeptidase; Procollagen C-proteinase; procollagen C-proteinase 3
Gene Aliases: BMP1; OI13; PCOLC; PCP; PCP2; TLD
UniProt ID: (Human) P13497, (Mouse) P98063
Entrez Gene ID: (Human) 649, (Rat) 83470, (Mouse) 12153
metalloendopeptidase activity
serine-type endopeptidase activity
cytokine activity
transforming growth factor beta receptor binding
calcium ion binding
protein binding
growth factor activity
peptidase activity
metallopeptidase activity
zinc ion binding
hydrolase activity
metal ion binding
metalloprotease
serine protease
skeletal system development
cartilage condensation
ossification
proteolysis
multicellular organism development
positive regulation of pathway-restricted SMAD protein phosphorylation
extracellular matrix disassembly
BMP signaling pathway
lipoprotein metabolic process
regulation of apoptotic process
regulation of MAPK cascade
cell development
SMAD protein signal transduction
positive regulation of cartilage development
cell differentiation
cartilage development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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