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Product Details
PA5-47222
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant human BMP-1/PCP Ala121-Gln730
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2609451
Product Specific Information
In direct ELISAs, approximately 10% cross-reactivity with recombinant human (rh) TLL-2 is observed, and less than 1% cross-reactivity with rhBMP-2, -3, -3b, -4, -5, -6, -7, -8, -9, -10, and -15 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BMP; BMP-1; Bone morphogenetic protein; Bone morphogenetic protein 1; FLJ44432; Mammalian tolloid protein; mTld; PCP; pCP-2; procollagen C-endopeptidase; Procollagen C-proteinase; procollagen C-proteinase 3
Gene Aliases: BMP1; OI13; PCOLC; PCP; PCP2; TLD
UniProt ID: (Human) P13497
Entrez Gene ID: (Human) 649
Molecular Function:
metalloprotease
serine protease
skeletal system development
cartilage condensation
ossification
proteolysis
multicellular organism development
positive regulation of pathway-restricted SMAD protein phosphorylation
extracellular matrix disassembly
BMP signaling pathway
lipoprotein metabolic process
regulation of apoptotic process
regulation of MAPK cascade
cell development
SMAD protein signal transduction
positive regulation of cartilage development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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