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          • Primary Antibodies ›
          • BMP4 Antibodies

          Fabgennix

          BMP4 Polyclonal Antibody

          View all (30) BMP4 antibodies

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          Cite BMP4 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          BMP4 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          BMP4 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          BMP4 Antibody (BMP-401AP) in WB

          Western blot of BMP4 antibody (BMP-401AP) with: Mouse spleen Mouse brain Apparent MW is 47 kDa. 1:250 dilution in DilObufferTM (FGI-1963). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          BMP4 Antibody in Western Blot (WB)

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          BMP4 Polyclonal Antibody

          Product Details

          BMP-401AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          ELISA (ELISA)

          1:10,000
          -

          Immunoprecipitation (IP)

          1:50-1:250
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide taken within amino acid region 184-197 on rat BMP4 protein, peptide was covalently modified.Sequence:VMKPPAPGHLIC
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5-1.5 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: BMP; BMP-2B; BMP-4; Bone morphogenetic protein; bone morphogenetic protein 2B; unnamed protein product

          View more View less

          Gene Aliases: Bmp-4; BMP2B; Bmp2b-1; BMP2B1; BOMPR4A; MCOPS6; OFC11; ZYME

          View more View less

          UniProt ID: (Human) P12644, (Mouse) P21275

          View more View less

          Entrez Gene ID: (Human) 652, (Mouse) 12159, (Rat) 25296

          View more View less

          Function(s)
          cytokine activity protein binding growth factor activity heparin binding co-receptor binding chemoattractant activity BMP receptor binding identical protein binding protein serine/threonine kinase activator activity
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter osteoblast differentiation ureteric bud development branching involved in ureteric bud morphogenesis kidney development mesonephros development positive regulation of protein phosphorylation positive regulation of endothelial cell proliferation endochondral ossification blood vessel endothelial cell proliferation involved in sprouting angiogenesis chondrocyte differentiation hematopoietic progenitor cell differentiation lymphoid progenitor cell differentiation myeloid leukocyte differentiation heart morphogenesis heart induction secondary heart field specification outflow tract septum morphogenesis membranous septum morphogenesis muscular septum morphogenesis outflow tract morphogenesis sinoatrial node development aortic valve morphogenesis pulmonary valve morphogenesis endocardial cushion development epithelial to mesenchymal transition involved in endocardial cushion formation cardiac right ventricle morphogenesis apoptotic process involved in endocardial cushion morphogenesis cardiac septum development type B pancreatic cell development mesoderm development positive regulation of cell proliferation negative regulation of cell proliferation post-embryonic development regulation of cell fate commitment gene expression positive regulation of gene expression negative regulation of gene expression positive regulation of epithelial to mesenchymal transition telencephalon development negative regulation of cell-cell adhesion monocyte differentiation macrophage differentiation positive regulation of cell migration positive regulation of bone mineralization BMP signaling pathway positive regulation of BMP signaling pathway positive regulation of epithelial cell differentiation positive regulation of protein binding positive regulation of collagen biosynthetic process negative regulation of T cell differentiation in thymus negative regulation of immature T cell proliferation in thymus tendon cell differentiation deltoid tuberosity development regulation of protein import into nucleus odontogenesis positive regulation of apoptotic process positive regulation of programmed cell death positive regulation of endothelial cell differentiation positive regulation of epidermal cell differentiation negative regulation of myoblast differentiation positive regulation of osteoblast differentiation positive regulation of ossification negative regulation of cell cycle negative regulation of mitotic nuclear division negative regulation of striated muscle tissue development negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter lung alveolus development intermediate mesodermal cell differentiation positive regulation of smooth muscle cell proliferation negative regulation of smooth muscle cell proliferation smooth muscle tissue development stem cell differentiation positive regulation of epithelial cell proliferation positive chemotaxis negative regulation of multicellular organismal process cardiac muscle cell differentiation positive regulation of cardiac muscle fiber development positive regulation of SMAD protein import into nucleus lung morphogenesis lung vasculature development bronchus development trachea development epithelial tube branching involved in lung morphogenesis epithelial cell proliferation involved in lung morphogenesis bud dilation involved in lung branching muscle tissue development coronary vasculature development positive regulation of cartilage development positive regulation of branching involved in lung morphogenesis pharyngeal arch artery morphogenesis negative regulation of thymocyte apoptotic process cellular response to BMP stimulus glomerular capillary formation negative regulation of glomerular mesangial cell proliferation nephric duct formation ureter morphogenesis negative regulation of mesenchymal cell proliferation involved in ureter development regulation of branching involved in ureteric bud morphogenesis negative regulation of branching involved in ureteric bud morphogenesis negative regulation of glomerulus development positive regulation of protein localization to nucleus positive regulation of p38MAPK cascade positive regulation of odontoblast differentiation regulation of miRNA transcription negative regulation of pri-miRNA transcription from RNA polymerase II promoter negative regulation of vascular smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell migration cardiac jelly development positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis negative regulation of metanephric S-shaped body morphogenesis negative regulation of metanephric comma-shaped body morphogenesis positive regulation of primary miRNA processing regulation of cardiac muscle cell differentiation negative regulation of extrinsic apoptotic signaling pathway skeletal system development angiogenesis ovarian follicle development blood vessel development eye development metanephros development mesoderm formation organ induction neural tube closure regulation of endothelial cell proliferation vasculature development renal system process germ cell development endoderm development mesodermal cell fate determination heart development anterior/posterior axis specification specification of organ position regulation of gene expression positive regulation of calcium ion transport into cytosol positive regulation of endothelial cell migration positive regulation of neuron projection development cardiac muscle hypertrophy in response to stress dorsal/ventral neural tube patterning telencephalon regionalization pituitary gland development erythrocyte differentiation lung development embryonic limb morphogenesis regulation of BMP signaling pathway negative regulation of BMP signaling pathway forebrain development positive regulation of vascular endothelial growth factor receptor signaling pathway negative regulation of chondrocyte differentiation cellular response to oxidative stress embryonic hindlimb morphogenesis specification of segmental identity, mandibular segment odontogenesis of dentin-containing tooth regulation of odontogenesis of dentin-containing tooth embryonic digit morphogenesis camera-type eye development regulation of MAPK cascade cell fate commitment regulation of cell differentiation positive regulation of cell differentiation positive regulation of neuron differentiation mesodermal cell differentiation camera-type eye morphogenesis embryonic morphogenesis anatomical structure formation involved in morphogenesis regulation of smooth muscle cell proliferation neuron fate commitment embryonic cranial skeleton morphogenesis embryonic skeletal system morphogenesis embryonic skeletal system development negative regulation of oligodendrocyte differentiation negative regulation of epithelial cell proliferation smooth muscle cell differentiation regulation of smooth muscle cell differentiation inner ear receptor cell differentiation lens induction in camera-type eye embryonic skeletal joint morphogenesis bone development cranial suture morphogenesis epithelium development trachea formation branching involved in prostate gland morphogenesis bud elongation involved in lung branching prostate gland morphogenesis mammary gland formation epithelial-mesenchymal cell signaling negative regulation of prostatic bud formation regulation of branching involved in prostate gland morphogenesis regulation of morphogenesis of a branching structure regulation of cartilage development positive regulation of hepatocyte differentiation regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade cellular response to growth factor stimulus cellular response to dexamethasone stimulus positive regulation of branching involved in ureteric bud morphogenesis sensory organ morphogenesis positive regulation of store-operated calcium channel activity positive regulation of mesenchymal stem cell proliferation positive regulation of pri-miRNA transcription from RNA polymerase II promoter positive regulation of morphogenesis of an epithelium positive regulation of endothelial cell apoptotic process response to mechanical stimulus response to estradiol response to retinoic acid response to testosterone tongue morphogenesis response to glucocorticoid anatomical structure regression retina development in camera-type eye lung lobe development cellular response to mechanical stimulus response to nitric oxide cellular response to thyroid hormone stimulus
          It has to be done as per old AB suggested Products section.

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