Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:3,000 | View 2 publications 2 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
Immunocytochemistry (ICC/IF) |
- | View 1 publication 1 publication |
Immunoprecipitation (IP) |
0.5-4.0 µg | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
BNIP1 Fusion Protein Ag8737 (1-228 aa encoded by BC010959) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.21 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MAAPQDVHV RICNQEIVKF DLEVKALIQD IRDCSGPLSA LTELNTKVKE KFQQLRHRIQ DLEQLAKEQD KESEKQLLLQ EVENHKKQML SNQASWRKAN LTCKIAIDNL EKAELLQGGD LLRQRKTTKE SLAQTSSTIT ESLMGISRMM AQQVQQSEEA MQSLVTSSRT ILDANEEFKS MSGTIQLGRK LITKYNRREL TDKLLIFLAL ALFLATVLYI VKKRLFPFL (1-228 aa encoded by BC010959 )
NIP1 (BNIP1) is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. Alternative splicing of this gene results in four products of unknown function. Transcript variant BNIP1 contains the entire coding region of the gene. This variant contains a fully conserved BH3 domain, which has been associated with pro-apoptotic function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BCL2/adenovirus E1B 19 kDa protein-interacting protein 1; BCL2/adenovirus E1B 19kDa interacting protein 1; BCL2/adenovirus E1B 19kDa-interacting protein 1; BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP1; BCL2/adenovirus E1B interacting protein 1, NIP1; BCL2/adenovirus E1B interacting protein 1-like 1; bnip1; bnip1 {ECO:0000312|EMBL:AAL50991.1, ECO:0000312|RGD:620799}; SNARE protein SEC20; Transformation-related gene 8 protein; TRG-8; Vesicle transport protein SEC20
Gene Aliases: 2010005M06Rik; 5930429G21Rik; BNIP1; Bnip1l1; NIP1; SEC20; SEC20L; TRG-8; TRG8
UniProt ID: (Human) Q12981, (Mouse) Q6QD59, (Rat) Q8VHI8
Entrez Gene ID: (Human) 662, (Mouse) 224630, (Rat) 140932
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