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Bioss
BNIP1 Polyclonal Antibody
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Product Details
BS-6681R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human BNIP1/TRG8, amino acids 51-150.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
NIP1 (BNIP1) is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. Alternative splicing of this gene results in four products of unknown function. Transcript variant BNIP1 contains the entire coding region of the gene. This variant contains a fully conserved BH3 domain, which has been associated with pro-apoptotic function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BCL2/adenovirus E1B 19 kDa protein-interacting protein 1; BCL2/adenovirus E1B 19kDa interacting protein 1; BCL2/adenovirus E1B 19kDa-interacting protein 1; BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP1; BCL2/adenovirus E1B interacting protein 1, NIP1; BCL2/adenovirus E1B interacting protein 1-like 1; BNIP1; bnip1 {ECO:0000312|EMBL:AAL50991.1, ECO:0000312|RGD:620799}; Nip1s1; Nip1s2; Nip1s3; SNARE protein SEC20; Transformation-related gene 8 protein; TRG-8; Vesicle transport protein SEC20
Gene Aliases: 2010005M06Rik; 5930429G21Rik; BNIP1; Bnip1l1; NIP1; SEC20; SEC20L; TRG-8; TRG8
UniProt ID: (Human) Q12981, (Mouse) Q6QD59, (Rat) Q8VHI8
Entrez Gene ID: (Human) 662, (Mouse) 224630, (Rat) 140932
transport
autophagy
apoptotic process
endoplasmic reticulum organization
protein transport
vesicle-mediated transport
endoplasmic reticulum membrane fusion
retrograde vesicle-mediated transport, Golgi to ER
response to activity
calcium-mediated signaling
response to starvation
negative regulation of apoptotic process
response to oxygen-glucose deprivation
execution phase of apoptosis
apoptotic process in response to mitochondrial fragmentation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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