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Invitrogen
BOK Polyclonal Antibody
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Product Details
PA5-70619
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the N-terminal region of human BOK
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This target displays homology in the following species: Cow: 100%; Dog: 93%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 86%
Target Information
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains all four BCL-2 like domains and is a pro-apoptotic BCL-2 protein identified in the ovary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bcl-2-like protein 9; Bcl-2-related ovarian killer protein; BCL2 family apoptosis regulator; BCL2 related ovarian killer; Bcl2-L-9; BOK, BCL2 family apoptosis regulator; hBOK
Gene Aliases: BCL2L9; BOK; BOKL
UniProt ID: (Human) Q9UMX3
Entrez Gene ID: (Human) 666
release of cytochrome c from mitochondria
apoptotic process
cellular component disassembly involved in execution phase of apoptosis
male gonad development
intrinsic apoptotic signaling pathway in response to DNA damage
regulation of autophagy
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of neuron apoptotic process
oligodendrocyte differentiation
protein oligomerization
neuron apoptotic process
regulation of cytosolic calcium ion concentration
negative regulation of mitochondrial depolarization
transmembrane transport
negative regulation of necroptotic process
intrinsic apoptotic signaling pathway by p53 class mediator
response to cisplatin
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of execution phase of apoptosis
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
regulation of chorionic trophoblast cell proliferation
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of PERK-mediated unfolded protein response
regulation of granulosa cell apoptotic process
positive regulation of intrinsic apoptotic signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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