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Product Details
17974-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BPHL Fusion Protein Ag12085 (1-194 aa encoded by BC037778)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.24 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
Immunogen sequence: MPRNLLYSL LSSHLSPHFS TSVTSAKVAV NGVQLHYQQT GEGDHAVLLL PGMLGSGETD FGPQLKNLNK KLFTVVAWDP RGYGHSRPPD RDFPADFFER DAKDAVDLMK ALKFKKVSLL GWSDGGITAL IAAAKYPSYI HKMVIWGANA YVTDEDSMIY EGIRDVSKWS ERTRKPLEAL YGWSLTLSPG WNAMA (1-194 aa encoded by BC037778)
Target Information
Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes. It is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: biphenyl hydrolase-like (serine hydrolase, breast epithelial mucin-associated antigen); Biphenyl hydrolase-like protein; Biphenyl hydrolase-related protein; Bph-rp; Breast epithelial mucin-associated antigen; MCNAA; Poly(ADP-ribose) glycohydrolase; VACVase; Valacyclovir hydrolase; valacyclovirase
Gene Aliases: 2010012D11Rik; 5730533B08Rik; AI115341; BPH-RP; BPHL; MCNAA; PARG; VACVASE
UniProt ID: (Human) Q86WA6, (Mouse) Q8R164
Entrez Gene ID: (Human) 670, (Rat) 361239, (Mouse) 68021
Molecular Function:
hydrolase
metabolite interconversion enzyme
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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