|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1/25 - 1/100|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues L(2587) I P S N D G K A G K E E F Y(2601) of human BRCA2 precursor protein, conjugated to Keyhole Limet Haemocyanin.|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred|
Predicted to react with cat, chimpanzee, dog, horse, mouse, rat and rhesus monkey based on sequence homology.
Heat-mediated antigen retrieval is recommended for the staining of paraffin sections.
Breast Cancer Type 2 susceptibility protein (BRCA2) is a tumour-suppressor protein reported to be involved in double-strand break repair, homologous recombination and S-phase checkpoint activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BRCA1/BRCA2-containing complex, subunit 2; BRCC2; breast and ovarian cancer susceptibility gene, early onset; breast and ovarian cancer susceptibility protein 2; breast cancer 2 tumor suppressor; breast cancer 2, early onset; Breast cancer type 2 susceptibility protein; BROVCA2; FACD; FAD; FAD1; FANCB; FANCD; FANCD1; Fanconi anemia group D1 protein; GLM3; mutant BRCA2; RP11-298P3.4
Gene Aliases: BRCA2; BRCC2; BROVCA2; FACD; FAD; FAD1; FANCD; FANCD1; GLM3; PNCA2; XRCC11
UniProt ID: (Human) P51587
Entrez Gene ID: (Human) 675
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