Applications | Tested Dilution | Publications |
---|---|---|
Immunohistochemistry (Paraffin) (IHC (P)) |
1/25 - 1/100 | - |
Immunohistochemistry (Frozen) (IHC (F)) |
Assay-dependent | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide corresponding to residues L(2587) I P S N D G K A G K E E F Y(2601) of human BRCA2 precursor protein, conjugated to Keyhole Limet Haemocyanin. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
5 mg/mL |
Purification |
Protein G |
Storage buffer |
PBS |
Contains |
0.09% sodium azide |
Storage conditions |
4°C or -20°C if preferred |
RRID |
AB_2067756 |
Predicted to react with cat, chimpanzee, dog, horse, mouse, rat and rhesus monkey based on sequence homology.
Heat-mediated antigen retrieval is recommended for the staining of paraffin sections.
Rabbit anti Human BRCA2 antibody recognizes human Breast Cancer Type 2 susceptibility protein (BRCA2), a tumour-suppressor protein reported to be involved in double-strand break repair, homologous recombination and S-phase checkpoint activation.
Breast Cancer Type 2 susceptibility protein (BRCA2) is a tumor-suppressor protein reported to be involved in double-strand break repair, homologous recombination and S-phase checkpoint activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: brca 2; brca-2; BRCA1/BRCA2-containing complex, subunit 2; breast and ovarian cancer susceptibility gene, early onset; breast and ovarian cancer susceptibility protein 2; breast cancer 2 tumor suppressor; breast cancer 2, early onset; Breast cancer type 2 susceptibility protein; FANCB; Fanconi anemia group D1 protein; mutant BRCA2; RP11-298P3.4
Gene Aliases: BRCA2; BRCC2; BROVCA2; FACD; FAD; FAD1; FANCD; FANCD1; GLM3; PNCA2; XRCC11
UniProt ID: (Human) P51587
Entrez Gene ID: (Human) 675
Molecular Function:
damaged DNA-binding protein
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