This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human BRF2. It recognizes a 50-60 kDa band in WB analysis.
This gene encodes one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. The product of this gene, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with the TATA-binding protein.
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Protein Aliases: B related factor 2; B-related factor 2; BRF 2; BRF-2; BRF2; BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like; BRFU; hBRFU; hTFIIIB50; RNA polymerase III transcription initiation factor BRFU; TFIIIB50; transcription factor IIB- related factor, TFIIIB50; Transcription factor IIIB 50 kDa subunit
Gene Aliases: 2700059M06Rik; 5730512K07Rik; AU018504; AU022602; BRF2; BRFU; PRO1470; TFIIIB50
Molecular Function: transcription factor