This gene encodes one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. The product of this gene, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with the TATA-binding protein.
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Protein Aliases: B-related factor 2; BRF-2; BRF2; BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like; BRFU; FLJ11052; hBRFU; hTFIIIB50; RNA polymerase III transcription initiation factor BRF2; RNA polymerase III transcription initiation factor BRFU; TFIIIB50; transcription factor IIB- related factor, TFIIIB50; Transcription factor IIIB 50 kDa subunit
Gene Aliases: BRF2; BRFU; PRO1470; TFIIIB50
UniProt ID: (Human) Q9HAW0
Entrez Gene ID: (Human) 55290
Molecular Function: transcription factor