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Search Thermo Fisher Scientific
BRPF1 (peregrin) is a component of the MOZ/MORF complex. This complex has histone H3 acetyltransferase activity. BRPF1 preferentially mediates histone H3-K23 acetylation and positively regulates the transcription of RUNX1 and RUNX2. Mutations affecting the gene can result in intellectual developmental disorder with dysmorphic facies and ptosis.
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Protein Aliases: Bromodomain and PHD finger-containing protein 1; Peregrin
Gene Aliases: 4833438B11Rik; 4930540D11Rik; Brpf1; Brpf2
UniProt ID: (Mouse) B2RRD7
Entrez Gene ID: (Mouse) 78783
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