|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human, Mouse|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 544-572 amino acids from the central region of human BRWD2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bromodomain and WD repeat domain containing 2; Bromodomain and WD repeat-containing protein 2; BRWD2; DR11; sensitization to ricin complex subunit 1; WD repeat domain 15; WD repeat-containing protein 11; WD repeat-containing protein 15; WDR15
Gene Aliases: 2900055P10Rik; AW489876; BRWD2; DR11; HH14; KIAA1351; mKIAA1351; SRI1; WDR11; WDR15
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