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Fabgennix
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression. [UniProt]
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Protein Aliases: BTB (POZ) domain containing 7; function-unknown protein 1; function-unkown protein 1; unnamed protein product
Gene Aliases: 5730507E09Rik; 8030448M07; E130118E17Rik; FUP1; mKIAA1525
UniProt ID: (Human) Q9P203, (Mouse) Q8CFE5
Entrez Gene ID: (Human) 55727, (Mouse) 238386
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