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Product Details
16482-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BTN2A2 Fusion Protein Ag9603 (281-523 aa encoded by BC014021)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VSICCIKKL QREKKILSGE KKVEQEEKEI AQQLQEELRW RRTFLHAADV VLDPDTAHPE LFLSEDRRSV RRGPYRQRVP DNPERFDSQP CVLGWESFAS GKHYWEVEVE NVMVWTVGVC RHSVERKGEV LLIPQNGFWT LEMFGNQYRA LSSPERILPL KESLCRVGVF LDYEAGDVSF YNMRDRSHIY TCPRSAFTVP VRPFFRLGSD DSPIFICPAL TGASGVMVPE EGLKLHRVGT HQSL (281-523 aa encoded by B C014021)
Target Information
Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is a type I receptor glycoprotein involved in lipid, fatty-acid and sterol metabolism. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: butyrophilin 2; Butyrophilin subfamily 2 member A2; butyrophilin, subfamily 2, member A2
Gene Aliases: BT2.2; BTF2; Btn2; BTN2.2; BTN2A2; D030063K05
UniProt ID: (Human) Q8WVV5, (Mouse) A4QPC6
Entrez Gene ID: (Human) 10385, (Mouse) 238555, (Rat) 306957
negative regulation of cellular metabolic process
negative regulation of activated T cell proliferation
negative regulation of cytokine secretion
negative regulation of phosphatidylinositol 3-kinase signaling
positive regulation of regulatory T cell differentiation
negative regulation of T cell receptor signaling pathway
negative regulation of protein kinase B signaling
negative regulation of ERK1 and ERK2 cascade
negative regulation of G1/S transition of mitotic cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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