Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Sequence homology: Cow: 79%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Rabbit: 93%
Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is a type I receptor glycoprotein involved in lipid, fatty-acid and sterol metabolism. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: butyrophilin 2; Butyrophilin subfamily 2 member A2; butyrophilin, subfamily 2, member A2
Gene Aliases: BT2.2; BTF2; BTN2.2; BTN2A2
UniProt ID: (Human) Q8WVV5
Entrez Gene ID: (Human) 10385
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