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|Tested species reactivity||Human , Mouse , Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant full length human BVES|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 50% glycerol|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:200|
|Western Blot (WB)||1:500-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody detects endogenous protein at a molecular weight of 41 kDa.
Purity is >95% by SDS-PAGE.
Blood vessel epicardial substance (BVES), also designated Popeye protein 1, is a transmembrane protein that plays a role in cell-cell interactions and adhesion, specifically at tight junctions. BVES is composed of an extracellular amino-terminus, three transmembrane domains and a cytoplasmic carboxyl-terminus. It is expressed in the developing coronary vascular system, specifically in the proepicardium, migrating epithelial epicardium, delaminated vasculogenic mesenchyme and vascular smooth muscle cells, where it functions to direct development in heart, epithelial and muscle cells during embryogenesis. BVES accumulates at points of cell-cell contact, such as filopodia and cell borders, and promotes adhesion prior to the arrival of E-cadherin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
blood vessel epicardial substance; HBVES; MGC42413; POP 1; POP1; POPDC 1; POPDC1; popeye 1; Popeye domain containing 1; Popeye domain containing protein 1; popeye domain-containing 1; popeye domain-containing protein 1; Popeye protein 1
BVES; HBVES; LGMD2X; mBVES; POP1; POPDC1