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Invitrogen
BVES Polyclonal Antibody
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Product Details
PA5-42932
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human BVES
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: YLIGKDITNK LYSLNDPTLN DKKAKKLEHQ LSLCTQISML EMRNSIASSS
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 82%; Zebrafish: 92%
Target Information
Blood vessel epicardial substance (BVES), also designated Popeye protein 1, is a transmembrane protein that plays a role in cell-cell interactions and adhesion, specifically at tight junctions. BVES is composed of an extracellular amino-terminus, three transmembrane domains and a cytoplasmic carboxyl-terminus. It is expressed in the developing coronary vascular system, specifically in the proepicardium, migrating epithelial epicardium, delaminated vasculogenic mesenchyme and vascular smooth muscle cells, where it functions to direct development in heart, epithelial and muscle cells during embryogenesis. BVES accumulates at points of cell-cell contact, such as filopodia and cell borders, and promotes adhesion prior to the arrival of E-cadherin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: blood vessel epicardial substance; MGC42413; POP 1; POPDC 1; Popeye domain-containing protein 1; Popeye protein 1; putative transmembrane protein; unnamed protein product
Gene Aliases: BVES; CARICK; HBVES; LGMD2X; LGMDR25; POP1; POPDC1
UniProt ID: (Human) Q8NE79
Entrez Gene ID: (Human) 11149
positive regulation of receptor recycling
regulation of heart rate
hematopoietic progenitor cell differentiation
response to ischemia
cell adhesion
heart development
muscle organ development
skeletal muscle tissue development
regulation of cell shape
striated muscle tissue development
vesicle-mediated transport
substrate adhesion-dependent cell spreading
positive regulation of locomotion
regulation of membrane potential
regulation of GTPase activity
vesicle docking
striated muscle cell differentiation
sinoatrial node cell development
cell migration involved in heart development
epithelial cell-cell adhesion
regulation of endocytic recycling
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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