Search
Fabgennix
Baboon Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
BAB-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Fruit fly
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
N-epitope Synthetic peptide corresponding to amino acid region 200-221 of Drosophila melanogaster protein. The peptide was covalently modified for conjugation.Synthetic peptide:CNKNENMKRIFEDYVPHRLTS
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Invovled in activin binding, GPCR kinase activity, serine threonine kinase activity and transforming growth factor beta receptor activity. The role of Baboon (Babo), a type I Activin receptor previously called Atr-I, in Drosophila development and characterize aspects of the Babo intracellular signal-transduction pathway. Genetic analysis of babo loss-of-function mutants and ectopic activation studies indicate that Babo signaling plays a role in regulating cell proliferation. In mammalian cells, activated Babo specifically stimulates Smad2-dependent pathways to induce TGF-beta/Activin-responsive promoters but not BMP-responsive elements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: activin A receptor 45A; activin type I receptor; babo; babo-PA; babo-PB; babo-PC; baboa; CG8224; CG8224-PA; CG8224-PB; CG8224-PC; G protein-coupled receptor kinase 3; Protein baboon; RE55648p; Receptor protein serine/threonine kinase; Receptor protein serine/threonine kinase babo
Gene Aliases: Atf1; ATR-1; ATR-I; Atr45A; AtrI; Bab; BABO; Babo-a; BaboA; CG8224; Dmel\CG8224; Dmel_CG8224; Gprk-3; Gprk3; l(2)44Fd; l(2)k16912; STK-E
UniProt ID: (Fruit fly) A1Z7L8
Entrez Gene ID: (Fruit fly) 35900
positive regulation of neuroblast proliferation
protein phosphorylation
nervous system development
axon guidance
eye-antennal disc morphogenesis
imaginal disc-derived wing morphogenesis
determination of adult lifespan
response to UV
negative regulation of autophagy
mushroom body development
activin receptor signaling pathway
glucose homeostasis
regulation of imaginal disc-derived wing size
R8 cell fate specification
positive regulation of imaginal disc growth
neuron development
dendrite morphogenesis
regulation of synapse structure or activity
pathway-restricted SMAD protein phosphorylation
SMAD protein signal transduction
cellular response to glucose stimulus
cellular response to growth factor stimulus
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support