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Proteintech
Band 3/AE 1 Polyclonal Antibody, CoraLite® Plus 488
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Product Details
CL488-28131
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Band 3/AE 1 fusion protein Ag27878
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MEELQDDYE DMMEENLEQE EYEDPDIPES QMEEPAAHDT EATATDYHTT SHPGTHKVYV ELQELVMDEK NQELRWMEAA RWVQLEENLG ENGAWGRPHL SHLTFWSLLE LRRVFTKGTV LLDLQETSLA GVANQLLDRF IFEDQIRPQD REELLRALLL KHSHAGELEA LGGVKPAVLT RSGDPSQPLL PQHSSLETQL F
Target Information
The Band 3 protein is the most abundant integral protein of human erythrocyte membranes and functions as the major anion transporter polypeptide of erythrocytes. Band 3 is a 90-100 kDa protein, its microheterogeneity is ascribed mainly to the structural heterogeneity of the carbohydrate moiety. The C-terminal portion of the molecule spans the membrane several times, and is responsible for anion transport. The N-terminal portion, comprising almost half of the polypeptide chain of Band 3, is located inside the red cell and interacts with cytoskeletal and cytoplasmic proteins such as ankyrin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AE 1; Anion exchange protein 1; anion exchanger-1; band 3 anion exchanger; Band 3 anion transport protein; CAMP; CD233; Diego blood group; erythrocyte membrane protein band 3; erythroid anion exchange protein; Froese blood group; MGC116750; MGC116753; MGC126619; MGC126623; solute carrier family 4 (anion exchanger), member 1 (Diego blood group); Solute carrier family 4 member 1; solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group); solute carrier family 4, anion exchanger, number 1; Swann blood group; UNIMAS band 3; AE1; unnamed protein product; Waldner blood group; Wright blood group; ZNF828
Gene Aliases: AE1; BND3; CD233; CHC; DI; EMPB3; EPB3; FR; RTA1A; SAO; SLC4A1; SPH4; SW; WD; WD1; WR
UniProt ID: (Human) P02730
Entrez Gene ID: (Human) 6521
inorganic anion exchanger activity
protein binding
cytoskeletal protein binding
anion transmembrane transporter activity
bicarbonate transmembrane transporter activity
chloride transmembrane transporter activity
antiporter activity
hemoglobin binding
ankyrin binding
protein homodimerization activity
protein anchor
chloride:bicarbonate antiporter activity
ion transport
anion transport
chloride transport
cellular ion homeostasis
blood coagulation
bicarbonate transport
phospholipid scrambling
negative regulation of urine volume
pH elevation
erythrocyte development
regulation of intracellular pH
transmembrane transport
protein localization to plasma membrane
chloride transmembrane transport
negative regulation of glycolytic process through fructose-6-phosphate
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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