Product References
Brevilin A promotes oxidative stress and induces mitochondrial apoptosis in U87 glioblastoma cells.
OncoTargets and therapy
Wang J,Li M,Cui X,Lv D,Jin L,Khan M,Ma T
Wed Mar 30 00:00:00 EDT 2022
Glutaminolysis Mediated by MALT1 Protease Activity Facilitates PD-L1 Expression on ABC-DLBCL Cells and Contributes to Their Immune Evasion.
Frontiers in oncology
Xia X,Zhou W,Guo C,Fu Z,Zhu L,Li P,Xu Y,Zheng L,Zhang H,Shan C,Gao Y
Thu Oct 01 00:00:00 EDT 2020
Anticancer effect of PP31J isolated from Physalis pubescens L. in human cervical carcinoma cells.
American journal of translational research
Zeng W,Wang Q,Chen L,Huang L,Zhao X
Tue Sep 29 00:00:00 EDT 2020
Protein kinase RNA-like ER kinase/eukaryotic translation initiation factor 2α pathway attenuates tumor necrosis factor alpha-induced apoptosis in nucleus pulposus cells by activating autophagy.
Journal of cellular physiology
Chen L,Liu L,Xie ZY,Wang F,Zhu L,Zhang C,Fan P,Sinkemani A,Hong X,Wu XT
Mon Jul 01 00:00:00 EDT 2019
Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.
Biochemical and biophysical research communications
Zhang Y,Li Q,Yu S,Zhu C,Zhang Z,Cao H,Xu J
Tue Feb 12 00:00:00 EST 2019
Alisol B-23-acetate, a tetracyclic triterpenoid isolated from Alisma orientale, induces apoptosis in human lung cancer cells via the mitochondrial pathway.
Biochemical and biophysical research communications
Wang J,Li H,Wang X,Shen T,Wang S,Ren D
Sat Nov 10 00:00:00 EST 2018
Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines.
Biological research
Meng M,Chen Y,Jia J,Li L,Yang S
Fri Aug 10 00:00:00 EDT 2018
MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway.
Cancer biology & therapy
Yin S,Du W,Wang F,Han B,Cui Y,Yang D,Chen H,Liu D,Liu X,Zhai X,Jiang C
Tue Apr 03 00:00:00 EDT 2018
Silencing Lin28 promotes apoptosis in colorectal cancer cells by upregulating let‑7c targeting of antiapoptotic BCL2L1.
Molecular medicine reports
Zhang H,Zong Y,Qiu G,Jia R,Xu X,Wang F,Wu D
Sun Apr 01 00:00:00 EDT 2018
The role of the long non-coding RNA TDRG1 in epithelial ovarian carcinoma tumorigenesis and progression through miR-93/RhoC pathway.
Molecular carcinogenesis
Chen S,Wang LL,Sun KX,Xiu YL,Zong ZH,Chen X,Zhao Y
Thu Feb 01 00:00:00 EST 2018
Oridonin induces G2/M cell cycle arrest and apoptosis in human oral squamous cell carcinoma.
European journal of pharmacology
Wang H,Zhu L,Feng X,Zhang H,Luo Q,Chen F
Wed Nov 15 00:00:00 EST 2017
DLEU1 contributes to ovarian carcinoma tumourigenesis and development by interacting with miR-490-3p and altering CDK1 expression.
Journal of cellular and molecular medicine
Wang LL,Sun KX,Wu DD,Xiu YL,Chen X,Chen S,Zong ZH,Sang XB,Liu Y,Zhao Y
Wed Nov 01 00:00:00 EDT 2017
The role of long non-coding RNA PCA3 in epithelial ovarian carcinoma tumorigenesis and progression.
Gene
Liu Y,Zong ZH,Guan X,Wang LL,Zhao Y
Mon Oct 30 00:00:00 EDT 2017
Targeting ERK enhances the cytotoxic effect of the novel PI3K and mTOR dual inhibitor VS-5584 in preclinical models of pancreatic cancer.
Oncotarget
Ning C,Liang M,Liu S,Wang G,Edwards H,Xia Y,Polin L,Dyson G,Taub JW,Mohammad RM,Azmi AS,Zhao L,Ge Y
Tue Jul 04 00:00:00 EDT 2017
SBI0206965, a novel inhibitor of Ulk1, suppresses non-small cell lung cancer cell growth by modulating both autophagy and apoptosis pathways.
Oncology reports
Tang F,Hu P,Yang Z,Xue C,Gong J,Sun S,Shi L,Zhang S,Li Z,Yang C,Zhang J,Xie C
Thu Jun 01 00:00:00 EDT 2017
Dehydrobruceine B enhances the cisplatin-induced cytotoxicity through regulation of the mitochondrial apoptotic pathway in lung cancer A549 cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Huang Z,Yang G,Shen T,Wang X,Li H,Ren D
Mon May 01 00:00:00 EDT 2017
Capsular Polysaccharide of Mycoplasma ovipneumoniae Induces Sheep Airway Epithelial Cell Apoptosis via ROS-Dependent JNK/P38 MAPK Pathways.
Oxidative medicine and cellular longevity
Jiang Z,Song F,Li Y,Xue D,Zhao N,Zhang J,Deng G,Li M,Liu X,Wang Y
Thu Apr 20 00:00:00 EDT 2017
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
International journal of molecular medicine
Wang H,Xu YS,Wang ML,Cheng C,Bian R,Yuan H,Wang Y,Guo T,Zhu LL,Zhou H
Sat Apr 01 00:00:00 EDT 2017
Inhibition of store-operated Ca2+ entry counteracts the apoptosis of nasopharyngeal carcinoma cells induced by sodium butyrate.
Oncology letters
Huang W,Ren C,Huang G,Liu J,Liu W,Wang L,Zhu B,Feng X,Shi J,Li J,Xia X,Jia W,Chen J,Chen Y,Jiang X
Wed Feb 01 00:00:00 EST 2017
Role of glycogen synthase kinase-3β inhibitor AZD1080 in ovarian cancer.
Drug design, development and therapy
Chen S,Sun KX,Feng MX,Sang XB,Liu BL,Zhao Y
Mon Dec 26 00:00:00 EST 2016
Up-regulation of granzyme B and perforin by staphylococcal enterotoxin C2 mutant induces enhanced cytotoxicity in Hepa1-6 cells.
Toxicology and applied pharmacology
Zhang G,Xu M,Zhang H,Song Y,Wang J,Zhang C
Thu Dec 15 00:00:00 EST 2016
Persistent Cytomegalovirus Infection in Amniotic Membranes of the Human Placenta.
The American journal of pathology
Tabata T,Petitt M,Fang-Hoover J,Zydek M,Pereira L
Tue Nov 01 00:00:00 EDT 2016
Persistent Cytomegalovirus Infection in Amniotic Membranes of the Human Placenta.
The American journal of pathology
Tabata T,Petitt M,Fang-Hoover J,Zydek M,Pereira L
Tue Nov 01 00:00:00 EDT 2016
Curcumin ameliorates high‑fat diet‑induced spermatogenesis dysfunction.
Molecular medicine reports
Mu Y,Yan WJ,Yin TL,Yang J
Sat Oct 01 00:00:00 EDT 2016
Lycopene inhibits the cell proliferation and invasion of human head and neck squamous cell carcinoma.
Molecular medicine reports
Ye M,Wu Q,Zhang M,Huang J
Sat Oct 01 00:00:00 EDT 2016
Propranolol sensitizes thyroid cancer cells to cytotoxic effect of vemurafenib.
Oncology reports
Wei WJ,Shen CT,Song HJ,Qiu ZL,Luo QY
Thu Sep 01 00:00:00 EDT 2016
Carnosic acid alleviates chronic alcoholic liver injury by regulating the SIRT1/ChREBP and SIRT1/p66shc pathways in rats.
Molecular nutrition & food research
Gao L,Shan W,Zeng W,Hu Y,Wang G,Tian X,Zhang N,Shi X,Zhao Y,Ding C,Zhang F,Liu K,Yao J
Thu Sep 01 00:00:00 EDT 2016
MicroRNA-490 inhibits tumorigenesis and progression in breast cancer.
OncoTargets and therapy
Zhao L,Zheng XY
Mon Aug 15 00:00:00 EDT 2016
HDAC6 promotes cell proliferation and confers resistance to gefitinib in lung adenocarcinoma.
Oncology reports
Wang Z,Tang F,Hu P,Wang Y,Gong J,Sun S,Xie C
Fri Jul 01 00:00:00 EDT 2016
Dioscin Induces Apoptosis in Human Cervical Carcinoma HeLa and SiHa Cells through ROS-Mediated DNA Damage and the Mitochondrial Signaling Pathway.
Molecules (Basel, Switzerland)
Zhao X,Tao X,Xu L,Yin L,Qi Y,Xu Y,Han X,Peng J
Sat Jun 04 00:00:00 EDT 2016
HIF-1α inhibition by 2-methoxyestradiol induces cell death via activation of the mitochondrial apoptotic pathway in acute myeloid leukemia.
Cancer biology & therapy
Zhe N,Chen S,Zhou Z,Liu P,Lin X,Yu M,Cheng B,Zhang Y,Wang J
Thu Jun 02 00:00:00 EDT 2016
Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through the PI3K/Akt pathway.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Li X,Song Y,Zhang P,Zhu H,Chen L,Xiao Y,Xing Y
Wed Jun 01 00:00:00 EDT 2016
MicroRNA-184 Modulates Doxorubicin Resistance in Osteosarcoma Cells by Targeting BCL2L1.
Medical science monitor : international medical journal of experimental and clinical research
Lin BC,Huang D,Yu CQ,Mou Y,Liu YH,Zhang DW,Shi FJ
Wed May 25 00:00:00 EDT 2016
EGCG induces lung cancer A549 cell apoptosis by regulating Ku70 acetylation.
Oncology reports
Li M,Li JJ,Gu QH,An J,Cao LM,Yang HP,Hu CP
Fri Apr 01 00:00:00 EDT 2016
Apoptosis induction of dehydrobruceine B on two kinds of human lung cancer cell lines through mitochondrial-dependent pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhao L,Wen Q,Yang G,Huang Z,Shen T,Li H,Ren D
Mon Feb 15 00:00:00 EST 2016
β-elemene sensitizes hepatocellular carcinoma cells to oxaliplatin by preventing oxaliplatin-induced degradation of copper transporter 1.
Scientific reports
Li X,Lin Z,Zhang B,Guo L,Liu S,Li H,Zhang J,Ye Q
Fri Feb 12 00:00:00 EST 2016
Overexpressed EDIL3 predicts poor prognosis and promotes anchorage-independent tumor growth in human pancreatic cancer.
Oncotarget
Jiang SH,Wang Y,Yang JY,Li J,Feng MX,Wang YH,Yang XM,He P,Tian GA,Zhang XX,Li Q,Cao XY,Huo YM,Yang MW,Fu XL,Li J,Liu DJ,Dai M,Wen SY,Gu JR,Hong J,Hua R,Zhang ZG,Sun YW
Tue Jan 26 00:00:00 EST 2016
Trichostatin A targets the mitochondrial respiratory chain, increasing mitochondrial reactive oxygen species production to trigger apoptosis in human breast cancer cells.
PloS one
Sun S,Han Y,Liu J,Fang Y,Tian Y,Zhou J,Ma D,Wu P
Thu Jan 14 00:00:00 EST 2016
Protective efficacy of carnosic acid against hydrogen peroxide induced oxidative injury in HepG2 cells through the SIRT1 pathway.
Canadian journal of physiology and pharmacology
Hu Y,Zhang N,Fan Q,Lin M,Zhang C,Fan G,Zhai X,Zhang F,Chen Z,Yao J
Sat Aug 01 00:00:00 EDT 2015
Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways.
Scientific reports
Liu J,Huang W,Ren C,Wen Q,Liu W,Yang X,Wang L,Zhu B,Zeng L,Feng X,Zhang C,Chen H,Jia W,Zhang L,Xia X,Chen Y
Fri Jul 24 00:00:00 EDT 2015
Chemical composition of total flavonoids from Polygonum amplexicaule and their pro-apoptotic effect on hepatocellular carcinoma cells: Potential roles of suppressing STAT3 signaling.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Xiang M,Su H,Hong Z,Yang T,Shu G
Mon Jun 01 00:00:00 EDT 2015
Chemical composition of total flavonoids from Polygonum amplexicaule and their pro-apoptotic effect on hepatocellular carcinoma cells: Potential roles of suppressing STAT3 signaling.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Xiang M,Su H,Hong Z,Yang T,Shu G
Mon Jun 01 00:00:00 EDT 2015
By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice.
Oncotarget
Dai W,Wang F,Lu J,Xia Y,He L,Chen K,Li J,Li S,Liu T,Zheng Y,Wang J,Lu W,Zhou Y,Yin Q,Abudumijiti H,Chen R,Zhang R,Zhou L,Zhou Z,Zhu R,Yang J,Wang C,Zhang H,Zhou Y,Xu L,Guo C
Sat May 30 00:00:00 EDT 2015
PNMA1 promotes cell growth in human pancreatic ductal adenocarcinoma.
International journal of clinical and experimental pathology
Jiang SH,He P,Ma MZ,Wang Y,Li RK,Fang F,Fu Y,Tian GA,Qin WX,Zhang ZG
Thu May 14 00:00:00 EDT 2015
An ESRG-interacting protein, COXII, is involved in pro-apoptosis of human embryonic stem cells.
Biochemical and biophysical research communications
Shi J,Ren C,Liu H,Wang L,Zhu B,Huang W,Liu W,Liu J,Liu Y,Xia X,Xu R,Jiang X
Fri May 01 00:00:00 EDT 2015
Oxaliplatin triggers necrosis as well as apoptosis in gastric cancer SGC-7901 cells.
Biochemical and biophysical research communications
Wu P,Zhu X,Jin W,Hao S,Liu Q,Zhang L
Fri May 01 00:00:00 EDT 2015
Potent effects of dioscin against liver fibrosis.
Scientific reports
Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J
Wed Apr 08 00:00:00 EDT 2015
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Medical oncology (Northwood, London, England)
Huang W,Liu J,Feng X,Chen H,Zeng L,Huang G,Liu W,Wang L,Jia W,Chen J,Ren C
Wed Apr 01 00:00:00 EDT 2015
Modulating the p66shc signaling pathway with protocatechuic acid protects the intestine from ischemia-reperfusion injury and alleviates secondary liver damage.
TheScientificWorldJournal
Ma L,Wang G,Chen Z,Li Z,Yao J,Zhao H,Wang S,Ma Z,Chang H,Tian X
Mon Jan 26 00:00:00 EST 2015
Galangin inhibits growth of human head and neck squamous carcinoma cells in vitro and in vivo.
Chemico-biological interactions
Zhu L,Luo Q,Bi J,Ding J,Ge S,Chen F
Fri Dec 05 00:00:00 EST 2014
Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis.
Transplantation
Tao X,Wan X,Xu Y,Xu L,Qi Y,Yin L,Han X,Lin Y,Peng J
Sat Sep 27 00:00:00 EDT 2014
Potent effects of flavonoid-rich extract from Rosa laevigata Michx fruit against hydrogen peroxide-induced damage in PC12 cells via attenuation of oxidative stress, inflammation and apoptosis.
Molecules (Basel, Switzerland)
Liu M,Xu Y,Han X,Liang C,Yin L,Xu L,Qi Y,Zhao Y,Peng J,Sun C
Thu Aug 07 00:00:00 EDT 2014
Salvianolic acid B protects against acute ethanol-induced liver injury through SIRT1-mediated deacetylation of p53 in rats.
Toxicology letters
Li M,Lu Y,Hu Y,Zhai X,Xu W,Jing H,Tian X,Lin Y,Gao D,Yao J
Tue Jul 15 00:00:00 EDT 2014
ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21((CIP1/WAF1)) in human cancer cells.
British journal of pharmacology
Li J,Chen Y,Wan J,Liu X,Yu C,Li W
Tue Jul 01 00:00:00 EDT 2014
KLF9, a transcription factor induced in flutamide-caused cell apoptosis, inhibits AKT activation and suppresses tumor growth of prostate cancer cells.
The Prostate
Shen P,Sun J,Xu G,Zhang L,Yang Z,Xia S,Wang Y,Liu Y,Shi G
Sun Jun 01 00:00:00 EDT 2014
Pao Pereira Extract Suppresses Castration-Resistant Prostate Cancer Cell Growth, Survival, and Invasion Through Inhibition of NFκB Signaling.
Integrative cancer therapies
Chang C,Zhao W,Xie B,Deng Y,Han T,Cui Y,Dai Y,Zhang Z,Gao J,Guo H,Yan J
Thu May 01 00:00:00 EDT 2014
Sine oculis homeobox homolog 1 promotes α5β1-mediated invasive migration and metastasis of cervical cancer cells.
Biochemical and biophysical research communications
Liu D,Zhang XX,Wan DY,Xi BX,Ma D,Wang H,Gao QL
Fri Apr 04 00:00:00 EDT 2014
Serine threonine kinase Pim-3 regulates STAT3 pathway to inhibit proliferation of human liver cancers.
International journal of clinical and experimental medicine
Wang J,Lao L,Zhao H,Huang Y
Thu Mar 06 00:00:00 EST 2014
Chemical composition of total flavonoids from Salvia chinensia Benth and their pro-apoptotic effect on hepatocellular carcinoma cells: potential roles of suppressing cellular NF-κB signaling.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Xiang M,Su H,Hu Y,Hu Y,Yang T,Shu G
Sun Dec 01 00:00:00 EST 2013
Synergistic anti-glioma effect of Hydroxygenkwanin and Apigenin in vitro.
Chemico-biological interactions
Wang Y,Xu YS,Yin LH,Xu LN,Peng JY,Zhou H,Kang W
Mon Nov 25 00:00:00 EST 2013
Anti-cancer effects of dioscin on three kinds of human lung cancer cell lines through inducing DNA damage and activating mitochondrial signal pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Wei Y,Xu Y,Han X,Qi Y,Xu L,Xu Y,Yin L,Sun H,Liu K,Peng J
Sun Sep 01 00:00:00 EDT 2013
Synergistic antitumour activity of sorafenib in combination with tetrandrine is mediated by reactive oxygen species (ROS)/Akt signaling.
British journal of cancer
Wan J,Liu T,Mei L,Li J,Gong K,Yu C,Li W
Tue Jul 23 00:00:00 EDT 2013
Role of Ku70 and Bax in epigallocatechin-3-gallate-induced apoptosis of A549 cells in vivo.
Oncology letters
Li JJ,Gu QH,Li M,Yang HP,Cao LM,Hu CP
Tue Jan 01 00:00:00 EST 2013
Suppression of the p66shc adapter protein by protocatechuic acid prevents the development of lung injury induced by intestinal ischemia reperfusion in mice.
The journal of trauma and acute care surgery
Wang GZ,Yao JH,Jing HR,Zhang F,Lin MS,Shi L,Wu H,Gao DY,Liu KX,Tian XF
Thu Nov 01 00:00:00 EDT 2012
CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells.
The Biochemical journal
Gong K,Xie J,Yi H,Li W
Tue May 01 00:00:00 EDT 2012
Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for hepatocellular carcinoma.
Free radical biology & medicine
Gong K,Li W
Thu Dec 15 00:00:00 EST 2011
Tetrandrine induces apoptosis by activating reactive oxygen species and repressing Akt activity in human hepatocellular carcinoma.
International journal of cancer
Liu C,Gong K,Mao X,Li W
Thu Sep 15 00:00:00 EDT 2011
Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Lin C,Jiang X,Dai Z,Guo X,Weng T,Wang J,Li Y,Feng G,Gao X,He L
Thu Oct 01 00:00:00 EDT 2009