|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Rat|
|Host / Isotype||Sheep|
|Immunogen||A synthetic peptide from human Beclin-1 conjugated to an immunogenic carrier protein|
|Storage buffer||whole serum|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:200-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
Reconstitute with 150 ul of distilled water.
Centrifuge to remove any insoluble material.
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. It may play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus. May play a role in autophagy. Ubiquitous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Compromised blood-brain barrier competence in remote brain areas in ischemic stroke rats at the chronic stage.
OSA00006W was used in immunohistochemistry to evaluate the integrity of blood-brain barrier competence in remote brain areas in ischemic stroke rats at the chronic stage
|Garbuzova-Davis S,Haller E,Williams SN,Haim ED,Tajiri N,Hernandez-Ontiveros DG,Frisina-Deyo A,Boffeli SM,Sanberg PR,Borlongan CV||The Journal of comparative neurology (522:3120)||2014|