Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Big Endothelin-1 is precursor of endothelin 1. Big endothelin-1 is cleaved to yield endothelin-1 via the activity of an endothelin-converting enzyme (ECE). Big Endothelin-1 can be hydrolyzed by chymase to generate endothelin 1 (1-21) in vitro. Endothelins are endothelium-derived vasoconstrictor peptides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Big endothelin-1; Endothelin-1; ET-1; PPET1; preproendothelin; Preproendothelin-1
Gene Aliases: ARCND3; EDN1; ET-1; ET1; HDLCQ7; PPET1; preproET; QME
UniProt ID: (Human) P05305, (Rat) P22388, (Mouse) P22387
Entrez Gene ID: (Human) 1906, (Rat) 24323, (Mouse) 13614
Molecular Function:
peptide hormone
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support