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Proteintech
Biglycan Polyclonal Antibody
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Product Details
16409-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Biglycan Fusion Protein Ag0683 (1-368 aa encoded by BC004244)
Conjugate
Form
Liquid
Concentration
0.22 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MWPLWRLVS LLALSQALPF EQRGFWDFTL DDGPFMMNDE EASGADTSGV LDPDSVTPTY SAMCPFGCHC HLRVVQCSDL GLKSVPKEIS PDTTLLDLQN NDISELRKDD FKGLQHLYAL VLVNNKISKI HEKAFSPLRK LQKLYISKNH LVEIPPNLPS SLVELRIHDN RIRKVPKGVF SGLRNMNCIE MGGNPLENSG FEPGAFDGLK LNYLRISEAK LTGIPKDLPE TLNELHLDHN KIQAIELEDL LRYSKLYRLG LGHNQIRMIE NGSLSFLPTL RELHLDNNKL ARVPSGLPDL KLLQVVYLHS NNITKVGVND FCPMGFGVKR AYYNGISLFN NPVPYWEVQP ATFRCVTDRL AIQFGNYKK (1-368 aa encoded by BC004244 )
Target Information
BGN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein is thought to function in connective tissue metabolism by binding to collagen fibrils and transferring growth factor-beta. It may promote neuronal survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Biglycan; bone/cartilage proteclycan 1; Bone/cartilage proteoglycan I; bone/cartilage proteoglycan-I; dermatan sulphate proteoglycan I; PG S1; PG-S1; small leucine-rich protein 1A; Small proteoglycan I (biglycan), bone (BSPG1) (bone/cartilage proteclycan 1 precursor)
Gene Aliases: BG; BGN; BSPG1; DSPG1; PG-S1; PGI; SLRR1A
UniProt ID: (Human) P21810, (Mouse) P28653, (Rat) P47853
Entrez Gene ID: (Human) 633, (Pig) 397396, (Mouse) 12111, (Rat) 25181
peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
blood vessel remodeling
negative regulation of protein kinase activity
biological_process
cytokine-mediated signaling pathway
extracellular matrix organization
glycosaminoglycan metabolic process
chondroitin sulfate biosynthetic process
chondroitin sulfate catabolic process
dermatan sulfate biosynthetic process
negative regulation of JAK-STAT cascade
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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