|Tested species reactivity||Human|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues E(381) I S V T S F T G C S V K Q A E D R F(399) of human BRS3 protein.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay dependent|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
PA3-302 detects BRS3 from human samples.
PA3-302 has been successfully used in Western blot and immunohistochemistry (paraffin) procedures. By Western blot, this antibody detects a ~50-70 kDa protein representing BRS3.
The PA3-302 immunogen is a synthetic peptide corresponding to residues E(381) I S V T S F T G C S V K Q A E D R F(399) of human BRS3 protein.
Bombesin receptor subtype-3 is often detected in prostate and pancreatic carcinomas as well as in pituitary adenomas. These are confined to the plasma membrane and uniformly present on nearly all tumor cells. These anti-peptide antibodies will facilitate identification of these tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Immunohistochemical detection of bombesin receptor subtypes GRP-R and BRS-3 in human tumors using novel antipeptide antibodies.
PA3-302 was used in immunocytochemistry, immunohistochemistry and western blot to investigate the expression of bombesin receptor 3 and gastrin-releasing peptide receptor in human tumors
|Schulz S,Röcken C,Schulz S||Virchows Archiv : an international journal of pathology (449:421)||2006|