This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
PA5-27392 targets BTK in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-27392 immunogen is recombinant fragment corresponding to a region within amino acids 429 and 659 of Human BTK.
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The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.
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Protein Aliases: agammaglobulinaemia tyrosine kinase; Agammaglobulinemia tyrosine kinase; AGMX1; ATK; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton tyrosine kinase; Bruton's tyrosine kinase; dominant-negative kinase-deficient Brutons tyrosine kinase; IMD1; PSCTK1; truncated Bruton agammaglobulinemia tyrosine kinase; Tyrosine-protein kinase BTK; tyrosine-protein kinase BTK isoform (lacking exon 13 to 17); tyrosine-protein kinase BTK isoform (lacking exon 14); XLA
Gene Aliases: AGMX1; AT; ATK; BPK; BTK; IMD1; PSCTK1; XLA
UniProt ID: (Human) Q06187
Entrez Gene ID: (Human) 695