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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||C1q isolated from the normal human serum.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C, store in dark, DO NOT FREEZE!|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-29720 detects C1q from human samples.
PA1-29720 has been successfully used in immunofluorescence applications.
The PA1-29720 immunogen is: C1q isolated from the normal human serum.
This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
complement C1q chain A; complement component 1, q subcomponent, A chain; complement component 1, q subcomponent, alpha polypeptide; complement component C1q, A chain