In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant mouse C1rLP is observed and less than 5% cross-reactivity with recombinant human (rh) C1R, rhC1S, and rhMASP-3 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
C1RL mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C1r-like protein; C1r-like serine protease analog protein; C1r-LP; CLSPa; Complement C1r subcomponent-like protein; complement C1r-like proteinase; complement component 1, r subcomponent-like
Gene Aliases: C1r-LP; C1RL; C1RL1; C1RLP; CLSPA
UniProt ID: (Human) Q9NZP8
Entrez Gene ID: (Human) 51279
Molecular Function: annexin calcium-binding protein calmodulin enzyme modulator hydrolase intracellular calcium-sensing protein peptide hormone protease protease inhibitor receptor serine protease signaling molecule