Search
Proteintech
C21orf45 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
25832-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
C21orf45 Fusion Protein Ag22922 (1-233 aa encoded by BC042917)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAGVRSLRC SRGCAGGCEC GDKGKCSDSS LLGKRLSEDS SRHQLLQKWA SMWSSMSEDA SVADMERAQL EEEAAAAEER PLVFLCSGCR RPLGDSLSWV ASQEDTNCIL LRCVSCNVSV DKEQKLSKRE KENGCVLETL CCAGCSLNLG YVYRCTPKNL DYKRDLFCLS VEAIESYVLG SSEKQIVSED KELFNLESRV EIEKSLTQME DVLKALQMKL WEAESKLSFA TCKS (1-233 aa encoded by BC042917)
Target Information
C21orf45, also named as MIS18A, C21orf46 and FASP1, is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. C21orf45 has dimer (~52 kDa) and heterodimer(~105 kDa) forms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FAPP1-associated protein 1; MIS18 kinetochore protein homolog A; Protein Mis18-alpha; unnamed protein product
Gene Aliases: 2610039C10Rik; 2810018N07Rik; B28; C21orf45; C21orf46; FASP1; hMis18alpha; MIS18A; MIS18alpha
UniProt ID: (Human) Q9NYP9, (Mouse) Q9CZJ6
Entrez Gene ID: (Human) 54069, (Mouse) 66578
cell cycle
chromosome segregation
mitotic nuclear division
CENP-A containing nucleosome assembly
regulation of DNA methylation
cell division
positive regulation of protein targeting to mitochondrion
heterochromatin assembly
protein localization to chromosome, centromeric region
pericentric heterochromatin organization
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support