Immunogen sequence: IHNPDEPETR DAWWAEIRQE IKSHAKALGC HAVVGYSEST SICEEVCILS ASGTAAVLNP RFLQDGTVEG CLEQRLEENL PTRCGFC
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 91%.
C2CD5 is required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. It binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 138 kDa C2 domain-containing phosphoprotein; C2 Calcium-dependent domain containing 5; C2 domain-containing phosphoprotein of 138 kDa; C2 domain-containing protein 5; C2CD5; CDP138; KIAA0528
Gene Aliases: C2CD5; CDP138; KIAA0528
UniProt ID: (Human) Q86YS7
Entrez Gene ID: (Human) 9847