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Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
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Protein Aliases: C3/C5 convertase; Complement C2; complement component C2
Gene Aliases: ARMD14; C2; CO2
UniProt ID: (Human) P06681
Entrez Gene ID: (Human) 717
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