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          • Primary Antibodies ›
          • Complement C2a Antibodies

          Bioss

          C2a Polyclonal Antibody

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          Cite C2a Polyclonal Antibody

          Additional Information:
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          C2a Polyclonal Antibody

          Product Details

          BS-10428R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:400
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human C2a, amino acids 401-500.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: C3/C5 convertase; Complement C2; complement component 2; complement component C2; unnamed protein product

          View more View less

          Gene Aliases: ARMD14; C2; CO2

          View more View less

          UniProt ID: (Human) P06681

          View more View less

          Entrez Gene ID: (Human) 717

          View more View less

          Function(s)
          serine-type endopeptidase activity protein binding peptidase activity serine-type peptidase activity hydrolase activity metal ion binding
          Process(es)
          complement activation, lectin pathway activation of membrane attack complex immune system process proteolysis complement activation complement activation, classical pathway response to nutrient opsonization response to bacterium killing of cells of other organism response to lipopolysaccharide innate immune response protein maturation response to thyroid hormone complement activation, GZMK pathway positive regulation of apoptotic cell clearance
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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