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C3a Receptor Polyclonal Antibody
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Product Details
BS-2955R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human C3a Receptor/C3aR, amino acids 401-482.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
C3AR1 is a receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. The receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. (Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: anaphylatoxin C3a receptor; C3a anaphylatoxin chemotactic receptor; C3a receptor; C3a-R; C3AR; complement component 3 receptor 1; Complement component 3a receptor 1; putative G protein-coupled receptor; similar to human C5A anaphylatoxin chemotactic receptor, Swiss-Prot Accession Number P21730; unnamed protein product
Gene Aliases: AZ3B; C3AR; C3AR1; C3R1; HNFAG09
UniProt ID: (Human) Q16581, (Rat) O55197, (Mouse) O09047
Entrez Gene ID: (Human) 719, (Rat) 84007, (Mouse) 12267
complement receptor activity
complement component C3a receptor activity
complement component C5a receptor activity
G-protein coupled receptor activity
complement component C3a binding
C3a anaphylatoxin receptor activity
signal transducer activity
anaphylatoxin receptor activity
G-protein coupled receptor
complement receptor mediated signaling pathway
positive regulation of immune system process
chemotaxis
inflammatory response
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood circulation
positive regulation of vascular endothelial growth factor production
positive regulation of macrophage chemotaxis
calcium-mediated signaling
complement component C5a signaling pathway
positive regulation of angiogenesis
positive regulation of neutrophil chemotaxis
tolerance induction to nonself antigen
regulation of blood pressure
positive regulation of cell migration
positive regulation of smooth muscle cell proliferation
positive regulation of glomerular mesangial cell proliferation
positive regulation of DNA biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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