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Invitrogen
C3a Receptor Polyclonal Antibody
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FIGURE: 1 / 2
C3a Receptor Antibody (PA5-29979) in WB
Western blot analysis of C3a Receptor was performed by separating 30 µg of whole cell extract by 10% SDS-PAGE. Proteins were transferred to a membrane and probed with a C3a Receptor Polyclonal Antibody (Product # PA5-29979) at a dilution of 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Product Details
PA5-29979
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human C3a receptor 1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.18 mg/mL
Amount
118 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: HL-60.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
C3AR1 is a receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. The receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. (Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C3a anaphylatoxin chemotactic receptor; C3a receptor; C3a-R; C3AR; complement component 3 receptor 1; complement component 3a receptor 1; putative G protein-coupled receptor; similar to human C5A anaphylatoxin chemotactic receptor, Swiss-Prot Accession Number P21730; unnamed protein product
Gene Aliases: AZ3B; C3AR; C3AR1; C3R1; HNFAG09
UniProt ID: (Human) Q16581, (Rat) O55197
Entrez Gene ID: (Human) 719, (Rat) 84007
complement receptor mediated signaling pathway
positive regulation of immune system process
chemotaxis
inflammatory response
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood circulation
positive regulation of vascular endothelial growth factor production
positive regulation of macrophage chemotaxis
calcium-mediated signaling
complement component C5a signaling pathway
positive regulation of angiogenesis
positive regulation of neutrophil chemotaxis
tolerance induction to nonself antigen
regulation of blood pressure
positive regulation of cell migration
positive regulation of smooth muscle cell proliferation
positive regulation of glomerular mesangial cell proliferation
positive regulation of DNA biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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