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Product Details
PA5-68482
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human C8A [aa 201-250].
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2692210
Product Specific Information
Predicted to react with Human samples.
Target Information
C8A is a component of the complement system and contains three polypeptide subunits: alpha, beta and gamma. C8A, in particular, contains the alpha subunit of C8 and is a constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself. Disease associated with C8A include Type 1 C8 deficiency and immunodeficiency due to C8A deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Complement component 8 subunit alpha; complement component 8, alpha polypeptide; Complement component C8 alpha chain
Gene Aliases: C8A
UniProt ID: (Human) Q9H130
Entrez Gene ID: (Human) 731
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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