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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Carbonic Anhydrase XIII Antibodies

          Proteintech

          CA13 Polyclonal Antibody

          1 Reference
          View all (9) Carbonic Anhydrase XIII antibodies

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          Datasheet
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          Datasheet
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          Questions & Answers

          Cite CA13 Polyclonal Antibody

          • Antibody Testing Data (19)
          CA13 Antibody in Immunocytochemistry (ICC/IF)
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          CA13 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 19

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          CA13 Antibody (16696-1-AP) in ICC/IF

          Immunofluorescent analysis of ( 10% Formaldehyde ) fixed NIH/3T3 cells using 16696-1-AP (CA13 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CA13 Antibody in Immunocytochemistry (ICC/IF)
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CA13 Antibody in Western Blot (WB)
          CA13 Antibody in Western Blot (WB)

          Product Details

          16696-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          CA13 Fusion Protein Ag10086 (1-262 aa encoded by BC052602)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.17 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MSRLSWGYR EHNGPIHWKE FFPIADGDQQ SPIEIKTKEV KYDSSLRPLS IKYDPSSAKI ISNSGHSFNV DFDDTENKSV LRGGPLTGSY RLRQVHLHWG SADDHGSEHI VDGVSYAAEL HVVHWNSDKY PSFVEAAHEP DGLAVLGVFL QIGEPNSQLQ KITDTLDSIK EKGKQTRFTN FDLLSLLPPS WDYWTYPGSL TVPPLLESVT WIVLKQPINI SSQQLAKFRS LLCTAEGEAA AFLVSNHRPP QPLKGRKVRA SFH (1-262 aa encoded by BC052602)

          Target Information

          Carbonic anhydrase XII (CA XII), encoded by the CA12 gene, is one of the enzyme isoforms in the carbonic anhydrase family that catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons. CA XII is a transmembrane protein expressed in various tissues, including the kidneys, intestines, and lungs, playing crucial roles in maintaining acid-base balance, pH regulation, and electrolyte transport. Its activity is significant in organs where fluid secretion and absorption are essential processes, impacting functions such as respiration and renal bicarbonate reabsorption. CA XII is involved in physiological processes like cell proliferation and differentiation by modulating the extracellular and intracellular pH, influencing tumor microenvironment dynamics. Aberrant expression of CA XII has been noted in several cancers, including breast and colorectal cancers, where it supports tumor growth and metastasis by maintaining the acid-base homeostasis conducive to cancer cell survival. Due to its surface expression and role in maintaining pH balance, CA XII is a target of interest for therapeutic interventions aiming to disrupt tumor progression and enhance the efficacy of cancer treatments.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: CA-XIII; Carbonate dehydratase XIII; Carbonic anhydrase 13; Carbonic anhydrase XIII

          View more View less

          Gene Aliases: 2310075C21Rik; CA13; Car13; CAXIII; RGD1560453

          View more View less

          UniProt ID: (Human) Q8N1Q1, (Mouse) Q9D6N1

          View more View less

          Entrez Gene ID: (Human) 377677, (Mouse) 71934, (Rat) 499566

          View more View less

          Function(s)
          carbonate dehydratase activity zinc ion binding lyase activity metal ion binding
          Process(es)
          one-carbon metabolic process bicarbonate transport
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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