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Product Details
13931-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:200-1:1,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
CA4 Fusion Protein Ag4960 (17-284 aa encoded by BC057792) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.21 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: ASAESHWCY EVQAESSNYP CLVPVKWGGN CQKDRQSPIN IVTTKAKVDK KLGRFFFSGY DKKQTWTVQN NGHSVMMLLE NKASISGGGL PAPYQAKQLH LHWSDLPYKG SEHSLDGEHF AMEMHIVHEK EKGTSRNVKE AQDPEDEIAV LAFLVEAGTQ VNEGFQPLVE ALSNIPKPEM STTMAESSLL DLLPKEEKLR HYFRYLGSLT TPTCDEKVVW TVFREPIQLH REQILAFSQK LYYDKEQTVS MKDNVRPLQQ LGQRTVIKS (17-284 aa encoded by BC057792)
Target Information
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary capillaries and proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CA IV; CA-IV; Carbonate dehydratase IV; Carbonic anhydrase 4; Carbonic anhydrase IV; carbonic dehydratase IV
Gene Aliases: AW456718; CA4; CAIV; Car4; RP17
UniProt ID: (Human) P22748, (Mouse) Q64444, (Rat) P48284
Entrez Gene ID: (Human) 762, (Mouse) 12351, (Rat) 29242
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