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Invitrogen
CABP1 Polyclonal Antibody
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FIGURE: 1 / 3
CABP1 Antibody (PA5-116830) in IHC (P)
Immunohistochemistry analysis of CABP1 in paraffin-embedded mouse kidney. Samples were incubated with CABP1 Polyclonal antibody (Product # PA5-116830) using a dilution of 1:50 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-116830
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CABP1 (NP_0010288491)
Conjugate
Form
Liquid
Concentration
1.08 mg/mL
Amount
108 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: Mouse brain, Rat brain
Immunogen sequence: MGGGDGAAFK RPGDGARLQR VLGLGSRREP RSLPAGGPAP RRTAPPPPGH ASAGPAAMSS HIAKSESKTS LLKAAAAAAS GGSRAPRHGP ARDPGLPSRR
Target Information
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CaBP1; Calbrain; calcium binding protein; calcium binding protein 5; Calcium-binding protein 1; Caldendrin
Gene Aliases: CABP1; CALBRAIN; caldendrin; HCALB_BR
UniProt ID: (Human) Q9NZU7, (Rat) O88751, (Mouse) Q9JLK7
Entrez Gene ID: (Human) 9478, (Rat) 171051, (Mouse) 29867
enzyme inhibitor activity
calcium channel regulator activity
calcium ion binding
protein binding
nuclear localization sequence binding
metal ion binding
calcium-dependent protein binding
protein domain specific binding
type 3 metabotropic glutamate receptor binding
protein homodimerization activity
ion channel binding
multicellular organism development
negative regulation of cell communication by electrical coupling
negative regulation of protein import into nucleus
regulation of synaptic plasticity
regulation of voltage-gated calcium channel activity
negative regulation of voltage-gated calcium channel activity
visual perception
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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