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CABP7 Antibody (PA5-53423) in WB
Western blot analysis of CABP7 in control (vector only transfected HEK293T lysate) and CABP7 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells). Samples were probed using a CABP7 Polyclonal Antibody (Product # PA5-53423).
Product Details
PA5-53423
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CABP7
Conjugate
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2639210
Product Specific Information
Immunogen sequence: LEEIREAFKV FDRDGNGFIS KQELGTAMRS LGYMPNEVEL EVIIQRLDMD GDGQVDFEEF VTLLGPKLST SGIPEKFHGT DFDTVFWKCD MQKLTVDELK RLLYDTFCEH LSMKDIENII MTEEESHLGT AEECPVDVET CSNQQIRQTC
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CaBP7; Calcium-binding protein 7; calneuron 2; Calneuron II; Calneuron-2
Gene Aliases: CABP7; CALN2
UniProt ID: (Human) Q86V35
Entrez Gene ID: (Human) 164633
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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