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Proteintech
CACNA1B Polyclonal Antibody
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Product Details
19681-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Amount
34.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BIII; Brain calcium channel III; calcium channel alpha12.2 subunit; calcium channel, L type, alpha-1 polypeptide; Calcium channel, L type, alpha-1 polypeptide isoform 5; calcium channel, voltage-dependent, L type, alpha 1B subunit; calcium channel, voltage-dependent, N type, alpha 1B subunit; Cav2.2 voltage-gated Ca2+ channel; voltage gated N-type calcium channel Ca(v)2.2; Voltage-dependent N-type calcium channel subunit alpha-1B; voltage-gated calcium channel alpha subunit Cav2.2; Voltage-gated calcium channel subunit alpha Cav2.2
Gene Aliases: alpha(1B); AW050276; AW060892; AW822256; BIII; CACH5; CACNA1B; CACNL1A5; CACNN; Cav2.2; Cchn1a; DYT23; NEDNEH
UniProt ID: (Human) Q00975, (Mouse) O55017
Entrez Gene ID: (Human) 774, (Mouse) 12287, (Rat) 257648
nucleotide binding
beta-amyloid binding
ion channel activity
voltage-gated calcium channel activity
calcium channel activity
calcium ion binding
protein binding
ATP binding
high voltage-gated calcium channel activity
metal ion binding
voltage-gated ion channel activity
protein C-terminus binding
protein phosphatase 2A binding
voltage-gated ion channel
ion transport
calcium ion transport
chemical synaptic transmission
ion transmembrane transport
modulation of synaptic transmission
transmembrane transport
calcium ion transmembrane transport
calcium ion import across plasma membrane
positive regulation of calcium ion-dependent exocytosis of neurotransmitter
response to amyloid-beta
positive regulation of neurotransmitter secretion
transport
neurotransmitter secretion
locomotory behavior
regulation of heart contraction
regulation of blood pressure
response to organic cyclic compound
sensory perception of pain
response to testosterone
regulation of ion transmembrane transport
response to pain
regulation of calcium ion transport
calcium ion import
membrane depolarization during action potential
response to ethanol
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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