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Proteintech
CACNA1I Polyclonal Antibody
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Product Details
19534-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
CaV3.3 encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by CaV3.3 is characterized by a slower activation and inactivation compared to other T-type calcium channels. CaV3.3 may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants of CaV3.3. Voltage-gated calcium channels (CaV) are present in the membrane of most excitable cells and mediate calcium influx in response to depolarization, an proteins such as CaV3.3 regulate intracellular processes such as contraction, secretion, neurotransmission and gene expression. Diseases associated with CACNA1I include Childhood Absence Epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ca(v)3.3; calcium channel, voltage-dependent, alpha 1I subunit; calcium channel, voltage-dependent, T type, alpha 1I subunit; Cav3.3; CaVT.3; hypothetical gene supported by NM_020084; low voltage-activated T-type calcium channel alpha-1 subunit (CACNA1I); low-voltage-activated calcium channel; low-voltage-activated calcium channel alpha13.3; RP1-172B20.4; voltage-dependent calcium channel; Voltage-dependent T-type calcium channel subunit alpha-1I; Voltage-gated calcium channel subunit alpha Cav3.3
Gene Aliases: Ca(V)3.3; CACNA1I; Cav3.3; KIAA1120; NEDSIS
UniProt ID: (Human) Q9P0X4, (Rat) Q9Z0Y8
Entrez Gene ID: (Human) 8911, (Rat) 56827, (Mouse) 239556
ion transport
calcium ion transport
signal transduction
neuronal action potential
sleep
ion transmembrane transport
transmembrane transport
calcium ion transmembrane transport
calcium ion import across plasma membrane
sperm motility
regulation of ion transmembrane transport
calcium ion transport into cytosol
calcium ion import
membrane depolarization during action potential
regulation of membrane potential
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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