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          • Primary Antibodies ›
          • CACNA2D1 Antibodies

          Proteintech

          CACNA2D1 Polyclonal Antibody

          6 References
          View all (8) CACNA2D1 antibodies

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          Cite CACNA2D1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (7)
          CACNA2D1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          CACNA2D1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          CACNA2D1 Antibody (27453-1-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded human brain tissue slide using 27453-1-AP (CACNA2D1 antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CACNA2D1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CACNA2D1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CACNA2D1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CACNA2D1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CACNA2D1 Antibody in Western Blot (WB)
          CACNA2D1 Antibody in Western Blot (WB)
          CACNA2D1 Antibody in Western Blot (WB)
          CACNA2D1 Polyclonal Antibody

          Product Details

          27453-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:4,000
          View 3 publications 3 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          -
          View 3 publications 3 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Pig, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          CACNA2D1 Fusion Protein Ag26190 (25-124 aa encoded by NM_000722)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Amount

          30 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MEPFPSAVT IKSWVDKMQE DLVTLAKTAS GVNQLVDIYE KYQDLYTVEP NNARQLVEIA ARDIEKLLSN RSKALVRLAL EAEKVQAAHQ WREDFASNEV VY (25-124 aa encoded by NM_000722)

          Target Information

          This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: alpha2delta-1; Calcium channel subunit alpha 2 delta (dihydropyridine - sensitive L-type); calcium channel, L type, alpha 2 polypeptide; calcium channel, voltage-dependent, alpha 2/delta subunit 1; DHP; dihydropyridine-sensitive calcium channel alpha 2; dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit; H_DJ0560O14.1; unnamed protein product; Voltage-dependent calcium channel subunit alpha-2/delta-1; Voltage-gated calcium channel subunit alpha-2/delta-1; WUGSC:H_DJ0560O14.1

          View more View less

          Gene Aliases: Ca(v)alpha2delta1; CACNA2; CACNA2D1; CACNL2A; CCHL2A; CCHLA2; DEE110; DHSCCA; LINC01112; lncRNA-N3; MHS3

          View more View less

          UniProt ID: (Human) P54289, (Mouse) O08532

          View more View less

          Entrez Gene ID: (Pig) 397377, (Human) 781, (Rat) 25399, (Mouse) 12293

          View more View less

          Function(s)
          voltage-gated calcium channel activity calcium channel activity metal ion binding voltage-gated calcium channel activity involved in cardiac muscle cell action potential voltage-gated calcium channel activity involved in bundle of His cell action potential protein binding voltage-gated ion channel activity calcium channel regulator activity voltage-gated ion channel
          Process(es)
          ion transport calcium ion transport ion transmembrane transport regulation of calcium ion transport regulation of ventricular cardiac muscle cell membrane repolarization calcium ion transport into cytosol calcium ion transmembrane transport via high voltage-gated calcium channel calcium ion transmembrane transport cardiac muscle cell action potential involved in contraction membrane depolarization during bundle of His cell action potential regulation of heart rate by cardiac conduction calcium ion import across plasma membrane regulation of membrane repolarization during action potential regulation of calcium ion transmembrane transport via high voltage-gated calcium channel cellular response to beta-amyloid regulation of ion transmembrane transport transport
          It has to be done as per old AB suggested Products section.

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