Search
Proteintech
CACNA2D1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
27453-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CACNA2D1 Fusion Protein Ag26190 (25-124 aa encoded by NM_000722)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MEPFPSAVT IKSWVDKMQE DLVTLAKTAS GVNQLVDIYE KYQDLYTVEP NNARQLVEIA ARDIEKLLSN RSKALVRLAL EAEKVQAAHQ WREDFASNEV VY (25-124 aa encoded by NM_000722)
Target Information
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: alpha2delta-1; Calcium channel subunit alpha 2 delta (dihydropyridine - sensitive L-type); calcium channel, L type, alpha 2 polypeptide; calcium channel, voltage-dependent, alpha 2/delta subunit 1; DHP; dihydropyridine-sensitive calcium channel alpha 2; dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit; H_DJ0560O14.1; unnamed protein product; Voltage-dependent calcium channel subunit alpha-2/delta-1; Voltage-gated calcium channel subunit alpha-2/delta-1; WUGSC:H_DJ0560O14.1
Gene Aliases: Ca(v)alpha2delta1; CACNA2; CACNA2D1; CACNL2A; CCHL2A; CCHLA2; DEE110; DHSCCA; LINC01112; lncRNA-N3; MHS3
UniProt ID: (Human) P54289, (Mouse) O08532
Entrez Gene ID: (Pig) 397377, (Human) 781, (Rat) 25399, (Mouse) 12293
voltage-gated calcium channel activity
calcium channel activity
metal ion binding
voltage-gated calcium channel activity involved in cardiac muscle cell action potential
voltage-gated calcium channel activity involved in bundle of His cell action potential
protein binding
voltage-gated ion channel activity
calcium channel regulator activity
voltage-gated ion channel
ion transport
calcium ion transport
ion transmembrane transport
regulation of calcium ion transport
regulation of ventricular cardiac muscle cell membrane repolarization
calcium ion transport into cytosol
calcium ion transmembrane transport via high voltage-gated calcium channel
calcium ion transmembrane transport
cardiac muscle cell action potential involved in contraction
membrane depolarization during bundle of His cell action potential
regulation of heart rate by cardiac conduction
calcium ion import across plasma membrane
regulation of membrane repolarization during action potential
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
cellular response to beta-amyloid
regulation of ion transmembrane transport
transport
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support