This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: EAWAEKFKVL ASNRTHQDQP QKCGPNSHCE MDCEVNNEDL LCVLIDDGGF LVLSNQNHQW DQVGRFFSEV DANLMLALYN
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 98%.
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha 2 delta calcium channel subunit; calcium channel, voltage-dependent, alpha 2/delta subunit 2; Cav alpha2/delta2; gene 26; Voltage-dependent calcium channel subunit alpha-2-2; Voltage-dependent calcium channel subunit alpha-2/delta-2; Voltage-dependent calcium channel subunit delta-2; Voltage-gated calcium channel subunit alpha-2/delta-2
Gene Aliases: CACNA2D; CACNA2D2; KIAA0558
UniProt ID: (Human) Q9NY47
Entrez Gene ID: (Human) 9254
Molecular Function: voltage-gated ion channel