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Invitrogen
CACNA2D2 Polyclonal Antibody
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Product Details
PA5-67202
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human CACNA2D2. Recombinant protein control fragment (Product #RP-107838).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TNTNLLFVVAE KPLCSQCEAG RLLQKETHSD GPEQCELVQR PRYRRGPHIC FDYNATEDTS DCGRGASFPP SLGVLVSLQL L
Highest antigen sequence identity to the following orthologs - mouse 100%, rat 99%.
Target Information
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha 2 delta calcium channel subunit; alpha2delta-2; calcium channel, voltage-dependent, alpha 2/delta subunit 2; Cav alpha2/delta2; gene 26; Voltage-dependent calcium channel subunit alpha-2/delta-2; Voltage-gated calcium channel subunit alpha-2/delta-2
Gene Aliases: CACNA2D; CACNA2D2; CASVDD; KIAA0558
UniProt ID: (Human) Q9NY47
Entrez Gene ID: (Human) 9254
ion transport
calcium ion transport
neuromuscular junction development
ion transmembrane transport
organ growth
regulation of multicellular organism growth
positive regulation of organ growth
muscle cell development
rhythmic synaptic transmission
calcium ion transmembrane transport
regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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