This antibody is predicted to react with mouse and rat based on sequence homology.
CACNA2D3 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.
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Protein Aliases: calcium channel alpha2-delta3 subunit; calcium channel, voltage-dependent, alpha 2/delta 3 subunit; calcium channel, voltage-dependent, alpha 2/delta subunit 3; CaV alpha2delta3; Voltage-dependent calcium channel subunit alpha-2-3; Voltage-dependent calcium channel subunit alpha-2/delta-3; Voltage-dependent calcium channel subunit delta-3; Voltage-gated calcium channel subunit alpha-2/delta-3
Gene Aliases: CACNA2D3; HSA272268
UniProt ID: (Human) Q8IZS8
Entrez Gene ID: (Human) 55799