Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain, rat brain.
Predicted reactivity: Mouse (97%), Rat (94%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Synaptogyrins comprise a family of tyrosine-phosphorylated proteins with two neuronal (synaptogyrins 1 and 3) isoforms. Previous studies have indicated that synaptogyrins are involved in the regulation of neurotransmitter release. Synaptogyrin 1 is an integral membrane protein ubiquitously expressed in the nervous system. Synaptogyrin has four transmembrane domains and an extended cytoplasmic tail but it is not glycosylated. Synaptogyrin 1 is a tyrosine-phosphorylated by c-src and possibly other tyrosine kinases. The function of Synaptogyrin 1 is not well understood, but it may be a useful marker for nerve terminals and diagnosing neuroendocrine tumors.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: beta 1 polypeptide; brain calcium channel beta 1 subunit; CAB1; CACNLB1; calcium channel; calcium channel beta 1 subunit; calcium channel beta-1 subunit; Calcium channel voltage-dependent subunit beta 1; calcium channel, L type, beta 1 polypeptide; calcium channel, voltage-dependent, beta 1 subunit; CCHLB1; dihydropyridine-sensitive L-type; dihydropyridine-sensitive L-type, calcium channel beta-1 subunit; L type; voltage-dependent calcium channel beta1 subunit; Voltage-dependent L-type calcium channel subunit beta-1
Gene Aliases: CAB1; CACNB1; CACNLB1; Cchb1; CCHLB1