This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Calcium Channel 1 is a protein encoded by the CACNB1 gene and belongs to the calcium channel beta subunit family. Calcium Channel 1 plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Calcium Channel 1 is involved in modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Diseases associated with Calcium Channel 1 protein dysfunction include malignant hyperthermia susceptibility.
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Protein Aliases: accessory voltage-dependent L-type calcium channel subunit; skeletal muscle L-type calcium channel beta1a subunit; beta 1 polypeptide; brain calcium channel beta 1 subunit; CAB1; CACNLB1; calcium channel; calcium channel beta 1 subunit; calcium channel beta-1 subunit; calcium channel beta1a subunit; Calcium channel voltage-dependent subunit beta 1; calcium channel, L type, beta 1 polypeptide; calcium channel, voltage-dependent, beta 1 subunit; CCHLB1; dihydropyridine receptor b1; dihydropyridine receptor beta 1a subunit; dihydropyridine receptor beta 1c subunit; dihydropyridine-sensitive L-type; dihydropyridine-sensitive L-type, calcium channel beta-1 subunit; L type; red; relaxed; voltage-dependent calcium channel beta1 subunit; voltage-dependent calcium channel L-type beta 1 isoform a; voltage-dependent calcium channel L-type beta 1 isoform c; Voltage-dependent L-type calcium channel subunit beta-1
Gene Aliases: BOS_18946; CAB1; CACNB1; CACNLB1; Cchb1; CCHLB1; zgc:91982