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Invitrogen
CACNB2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-68699
Product Specifications
Species Reactivity
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the middle region of rat Calcium Channel 2
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Target Information
The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAB1; CAB2; CACNB2c; CACNB2e; CACNLB1; calcium channel voltage-dependent subunit beta 2; calcium channel, voltage-dependent, beta 2 subunit; Cavb2i; CCHLB1; ion channel; MGC138502; MGC138504; MGC41896; voltage-gated calcium channel beta2i subunit
Gene Aliases: Cacnlb2
UniProt ID: (Rat) Q8VGC3
Entrez Gene ID: (Rat) 116600
voltage-gated calcium channel activity
calcium channel regulator activity
protein binding
high voltage-gated calcium channel activity
protein kinase binding
protein domain specific binding
actin filament binding
phosphoprotein binding
voltage-gated calcium channel activity involved in cardiac muscle cell action potential
voltage-gated calcium channel activity involved in AV node cell action potential
voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels
calcium ion transport
chemical synaptic transmission
visual perception
positive regulation of calcium ion transport
calcium ion import
calcium ion transmembrane transport
protein localization to plasma membrane
membrane depolarization during AV node cell action potential
regulation of heart rate by cardiac conduction
membrane depolarization during atrial cardiac muscle cell action potential
regulation of presynaptic cytosolic calcium ion concentration
regulation of voltage-gated calcium channel activity
positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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