This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: DYWLYTRALI CNTTNLTAGG DDGTPHRGGG GASEKKDPGG LTHSGL
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.
Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: calcium channel, voltage-dependent, gamma subunit 8; CaVGamma8; Neuronal voltage-gated calcium channel gamma-8 subunit; TARP gamma-8; Transmembrane AMPAR regulatory protein gamma-8; Voltage-dependent calcium channel gamma-8 subunit
Gene Aliases: CACNG6; CACNG8
UniProt ID: (Human) Q8WXS5
Entrez Gene ID: (Human) 59283
Molecular Function: voltage-gated ion channel